• 創造そうぞう — creation
• 創業そうぎょう — founding a business
• 創作そうさく — literary/artistic creation
• 創設そうせつ — establishment
• 独創どくそう — originality

創 is a phono-semantic compound made from 倉 (phonetic) and 刂 (sword radical). Originally representing “cutting to begin something,” it later evolved to symbolize the act of starting or creating something new.

新あたらしい会社かいしゃを 創つくりました。
We started a new company.

彼かれは 創造力そうぞうりょくが 豊ゆたかです。
He has a rich imagination.

The most common on-yomi reading is ソウ, used in many compound words. The kun-yomi つくる is used when the kanji stands alone or in native phrases.